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Pristiq or the generic Desvenlafaxine Succinate is an antidepressant that belongs to a class of drugs called selective serotonin and norepinephrine reuptake inhibitors (SNRIs). Pristiq should be taken at approximately the same time each day. The recommended dose for Pristiq is 50 mg once daily, with or without food. Partnership for Prescription Assistance helps. For help with the PRISTIQ Savings Offer, call 1-855-440-6852 or write: PRISTIQ Savings Offer, 2250 Perimeter Park Drive, Suite 300, Morrisville, NC 27560 If your pharmacy does not participate, you may be able to submit a request for a rebate in connection with this Savings Offer 90. Medication Guide ; for Healthcare professionals: PRISTIQ U. SNRIs are typically used to treat depression Prescription assistance programs (PAPs) are available across the country. For more information, call 1-800-444-4106 Note: If you are a New York prescriber, please attach state prescription form. 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